Comparison of anterior segment parameters in myopia with and without primary open-angle glaucoma

To compare anterior segment parameters between myopes with and without primary open-angle glaucoma using Pentacam scheimpflug tomography.

This was a single-center retrospective cross-sectional study. Records of patients examined with a Pentacam scheimpflug tomographer (Wavelight-Allegro Oculyzer, GmbH, Erlangen, Germany) were reviewed. Variables studied were recorded from the topographic map and included anterior chamber angle, anterior chamber volume, anterior chamber depth, keratometric readings, and corneal thickness. A general linear model for age-and spherical equivalent refraction-adjusted intergroup comparisons of the anterior segment parameters was conducted.

The study included myopes previously diagnosed with primary open-angle glaucoma (POAG) [Mild defect, n = 81; Moderate-severe defect, n = 50] and non-glaucomatous myopes (n = 247). The results revealed a smaller anterior chamber angle, shallower anterior chamber depth, and flatter cornea curvature in the mildly glaucomatous group compared to the non-glaucomatous group (p < 0.05). Smaller anterior chamber angle, shallower anterior chamber depth, and thinner cornea thickness were also observed in the moderate-severely glaucomatous group compared to the non-glaucomatous group (p < 0.05).

Glaucomatous damage in myopic patients with POAG was associated with comparatively small anterior chamber angle, shallow anterior chamber depth, flat cornea curvature, and thin cornea.