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Updated: Aug 15, 2025

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP
Published on: January 27, 2010
Postoperative opioid protocol: A 5-year resident-led effort to standardize prescribing patterns
Charles Meyer1, Élan Bresslour-Rashap2, Jessica Winters1
1Naval Medical Center Portsmouth, Department of Otolaryngology-Head and Neck Surgery, Portsmouth, VA, United States of America.
A 5-year resident-led initiative standardized opioid prescribing in Otolaryngology, significantly reducing opioid use, refills, and costs. This initiative improved pain management and prescribing practices for postoperative patients.
Area of Science:
- Otolaryngology
- Pain Management
- Pharmacology
Background:
- Surgeon prescribing preferences and resident comfort levels create disparities in opioid prescribing.
- Standardizing postoperative prescription practices is crucial for consistent patient care.
Purpose of the Study:
- To update on the expanded scope of a 5-year resident-led initiative to standardize postoperative prescription practices.
- To evaluate the impact of the Expanded Postoperative Analgesia Protocol on opioid prescribing patterns and patient outcomes.
Main Methods:
- Retrospective review of 12 months pre-protocol and 48 months post-protocol implementation.
- Comparison of Pre-Protocol and Expanded Protocol cohorts using ANOVA, chi-squared, and Fisher Exact tests.
- Covariate analysis using ANCOVA and binary logistic regression; cost impact calculated using medication spending data.
Main Results:
- Significant reduction in combination opioid medications (91.3% to 3.8%).
- 66% reduction in average morphine milligram equivalents per patient.
- 74% reduction in postoperative medication costs and 68% reduction in medication refills.
Conclusions:
- Purposeful standardization led to sustained changes in departmental prescribing practices.
- The initiative resulted in reduced variability, lower costs, and improved opioid management.
- The protocol yielded superior pain control for postoperative patients.
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