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Updated: Aug 15, 2025
09:31
In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
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No difference in renal function outcomes for patients with oncocytoma managed with active surveillance vs. partial
Kevin B Ginsburg1, Marshall Strother2, Jared P Schober1
1Department of Surgical Oncology, Division of Urologic Oncology, Fox Chase Cancer Center, Philadelphia PA.
Urologic Oncology
|December 31, 2022
Summary
Active surveillance and partial nephrectomy show similar long-term renal function outcomes for oncocytoma patients. Surgery for oncocytomas should be reserved for select cases, prioritizing kidney function preservation.
Area of Science:
- Nephrology
- Urologic Oncology
Background:
- Oncocytomas are benign kidney tumors often managed surgically.
- Assessing long-term renal function is crucial for treatment decisions.
- Comparing active surveillance (AS) and partial nephrectomy (PN) impacts patient management.
Approach:
- Retrospective review of 114 oncocytoma patients (2000-2020).
- Utilized generalized estimating equations (GEE) to analyze estimated glomerular filtration rate (eGFR) and chronic kidney disease (CKD) progression.
- Compared renal function outcomes between AS and PN groups.
Key Points:
- AS patients were older with lower baseline eGFR compared to PN patients.
- No significant difference in predicted longitudinal eGFR between AS and PN groups.
- Similar predicted probability of progression to CKD stage III or greater for both management strategies.
Conclusions:
- Active surveillance and partial nephrectomy yield comparable long-term renal function outcomes in oncocytoma patients.
- These findings support reserving partial nephrectomy for select oncocytoma cases.
- Prioritizing kidney function preservation is key in oncocytoma management.
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