Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Pharmacokinetic Models: Comparison and Selection Criterion

Pharmacokinetic Models: Comparison and Selection Criterion

Physiological and compartmental models are valuable tools used in studying biological systems. These models rely on differential equations to maintain mass balance within the system, ensuring an accurate representation of the dynamic processes at play.
Physiological models take a detailed approach by considering specific molecular processes. They can predict drug distribution, metabolism, and elimination changes, providing a comprehensive understanding of how drugs interact with the body.

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Cost-effectiveness of N-terminal pro-B-type natriuretic peptide thresholds for echocardiography referral in primary care heart failure management.

Heart (British Cardiac Society)·2026

Same author

Cost-effectiveness of osteoporotic fracture risk assessment in people with intellectual disabilities: a UK NHS modelling study.

BMJ open·2026

Same author

Perceptions and Experiences of Co-Produced Positive Behaviour Support Training in Community-Based Services and Organisations for Children With Intellectual Disabilities and Behaviours That Challenge: A Qualitative Multiple Case Study Design.

Journal of applied research in intellectual disabilities : JARID·2026

Same author

Rasch analysis of the self-reported PedsQL™ 4.0 Generic Core Scales by Australian children.

Health and quality of life outcomes·2025

Same author

Adopting and embedding home sensors in social care: findings from a mixed methods, rapid evaluation.

NIHR open research·2025

Same author

Glycaemic control in labour with diabetes: GILD, a scoping study.

Health technology assessment (Winchester, England)·2025

Search research articles

Related Experiment Video

Updated: Aug 15, 2025

Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model

Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model

Published on: September 8, 2023

Interpreting decision-analytic modelling-based economic evaluations in orthopaedics.

Stavros Petrou¹, May Ee Png¹, David Metcalfe²

¹Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.

The Bone & Joint Journal

|January 1, 2023

Summary

This summary is machine-generated.

Economic evaluation models assess healthcare interventions. This guide helps interpret economic evaluations of orthopaedic treatments, improving decision-making for readers and reviewers.

Keywords:

Australian Orthopaedic Association National Joint Replacement Registry Decision modelling Economic evaluation displaced femoral neck fractures dual-mobility components meniscal tear orthopaedic research orthopaedic surgery randomized controlled trial sensitivity analysis statistical analysis total hip arthroplasty

More Related Videos

A Mouse Model of Orthopedic Surgery to Study Postoperative Cognitive Dysfunction and Tissue Regeneration

A Mouse Model of Orthopedic Surgery to Study Postoperative Cognitive Dysfunction and Tissue Regeneration

Published on: February 27, 2018

Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach

Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach

Published on: January 24, 2018

Related Experiment Videos

Last Updated: Aug 15, 2025

Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model

Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model

Published on: September 8, 2023

A Mouse Model of Orthopedic Surgery to Study Postoperative Cognitive Dysfunction and Tissue Regeneration

A Mouse Model of Orthopedic Surgery to Study Postoperative Cognitive Dysfunction and Tissue Regeneration

Published on: February 27, 2018

Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach

Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach

Published on: January 24, 2018

Area of Science:

Health Economics
Orthopaedic Surgery
Decision Analysis

Background:

Economic evaluation is crucial for assessing healthcare interventions.
Decision-analytic models are commonly used for economic evaluations in healthcare.
Numerous economic evaluations of orthopaedic interventions have been published.

Purpose of the Study:

To provide guidance for interpreting economic evaluations of orthopaedic interventions.
To assist readers, reviewers, and decision-makers in understanding complex modelling evidence.
To highlight key issues in decision-analytic modelling for orthopaedic surgery.

Main Methods:

The study is an annotation and review of existing literature.
It synthesizes common challenges and best practices in economic modelling.
Focuses on parameter inputs, mathematical techniques, and software application.

Main Results:

Decision-analytic models synthesize diverse data for cost-effectiveness analysis.
Interpreting these models requires understanding their structure and inputs.
Potential issues in modelling can affect the reliability of economic evaluations.

Conclusions:

Clear interpretation of economic evaluations is vital for informed orthopaedic healthcare decisions.
This annotation offers a framework for critically appraising modelling studies.
Enhanced understanding facilitates better resource allocation in orthopaedics.