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Multiple Distinct Neoplasms in a North African Hedgehog (Atelerix algirus).

Francisco Rodríguez1, Juan D Hernández2, Jorge Orós1

  • 1Veterinary Histology and Pathology, Veterinary School, Universidad de Las Palmas de Gran Canaria, Arucas, Spain.

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|January 1, 2023
PubMed
Summary

This study details a North African hedgehog with multiple, distinct tumors across different organ systems, including a mast cell tumor, oral cancers, and adrenal myelolipomas. This case highlights the complex neoplastic burden possible in hedgehogs.

Keywords:
hedgehoghistiocytic sarcomamast cell tumormyelolipomasquamous cell carcinoma

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Area of Science:

  • Veterinary Pathology
  • Oncology
  • Comparative Medicine

Background:

  • Neoplasms are a recognized concern in hedgehogs.
  • Multiple concurrent tumors in a single hedgehog are rare but documented.
  • This report focuses on a unique case in *Atelerix algirus*.

Observation:

  • A 3.5-year-old female hedgehog presented with a dermal mast cell tumor, successfully excised.
  • Six months later, the hedgehog developed oral masses, leading to systemic decline.
  • Necropsy revealed squamous cell carcinoma, histiocytic sarcoma, and adrenal myelolipomas.

Findings:

  • The dermal mast cell tumor was well-differentiated with no metastasis.
  • Oral squamous cell carcinoma showed metastasis to the lungs.
  • Multiple myelolipomas were identified in the adrenal glands.

Implications:

  • This case represents the first documented instance of myelolipoma in hedgehogs.
  • It also describes multiple concurrent neoplasms of diverse cellular origins in various organ systems within a single hedgehog.
  • This finding expands our understanding of neoplastic complexity and potential disease progression in this species.