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Updated: Aug 15, 2025

Visualization of Metabolites Identified in the Spatial Metabolome of Traditional Chinese Medicine Using DESI-MSI
Published on: December 16, 2022
Preparation methods, structural characteristics, and biological activity of polysaccharides from Salvia miltiorrhiza:
Yuanyuan Li1, Xin Zhang1, Yining Li1
1School of Pharmaceutical Sciences, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China.
Ethnopharmacological Relevance:
Salvia miltiorrhiza is a traditional Chinese medicine with the application of more than a two-thousand-year history. It is a common medicine used in the clinical treatment of cardiovascular and cerebrovascular diseases and is listed as the top grade in Shennong's Classic of Materia Medica. Polysaccharide is an important chemical component of Salvia miltiorrhiza and has a variety of biological activities.
Aim Of The Study:
In this review, we summarized the preparation methods, structural characteristics, and biological activities of Salvia miltiorrhiza polysaccharides, as well as discussed current research problems, providing support for further research, development, and utilization.
Materials And Methods:
By inputting the search term "Salvia miltiorrhiza polysaccharides", relevant research information was obtained from databases such as Google Scholar, PubMed, VIP, Web of Science, and China Knowledge Network (CNKI).
Results:
It has been found that the monosaccharide composition of Salvia miltiorrhiza polysaccharides containing glucose (Glc), galactose (Gal), mannose (Man), and arabinose (Ara) has antioxidant, anti-tumor, liver protection, and other activities.
Conclusions:
We summarized the preparation methods, structural information, and biological activities of Salvia miltiorrhiza polysaccharides in this review and discussed the issues that are currently being researched. Although this product has a wide range of biological activities and has high development and utilization potential, its structure information and structure-activity relationship require further investigation.

