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Related Experiment Videos

Allergic and disergic children rhinopathy.

D Alpini1, E Corgiolu, P L Pozzi

  • 1Divisione ORL, Ospedale Busto Arsizio (VA), Italia.

La Pediatria Medica E Chirurgica : Medical and Surgical Pediatrics
|March 1, 1987
PubMed
Summary
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This study investigated obstructive rhinopathy in children, finding decreased secretory IgA levels in most cases. Allergy components were identified in some children, suggesting a link between nasal obstruction and immune factors.

Area of Science:

  • Pediatric Otolaryngology
  • Allergology
  • Immunology

Background:

  • Obstructive rhinopathy in children presents with nasal obstruction, hypertrophic adenoids, and associated otologic issues like otitis media.
  • The etiology of obstructive rhinopathy is complex, potentially involving allergic and immune system factors.

Purpose of the Study:

  • To investigate the clinical presentation and potential etiologies of obstructive rhinopathy in 42 children.
  • To assess the role of allergic sensitization and immune markers, specifically secretory IgA, in children with nasal obstruction.

Main Methods:

  • Utilized rhinomanometry, tympanometry, and tubotympanometry to evaluate nasal stenosis and otologic conditions.
  • Performed allergy testing (skin prick tests, IgE assays) and analyzed nasal smears and secretory IgA levels for etiological insights.

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Main Results:

  • Decreased secretory IgA levels were observed in 39 out of 42 children.
  • Positive allergy indicators (skin tests or IgE) were found in 14 children, with environmental or familial history noted in some.
  • Nasal smears showed neutrophilia in 30 children, lymphocytosis in 2, and eosinophilia in 5.

Conclusions:

  • Obstructive rhinopathy in children is frequently associated with significantly reduced secretory IgA levels.
  • While allergic components are present in a subset of cases, immune dysregulation, particularly low secretory IgA, appears prevalent.
  • Further research is warranted to explore the immunopathogenesis of obstructive rhinopathy and its link to recurrent otitis media.