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The link between reversible cerebral vasoconstriction syndrome and transient global amnesia
Rahul Chandra1, Harneel Singh Saini2, Kaitlyn N Palmer1
1Neurology, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Headache
|January 2, 2023
Summary
Reversible cerebral vasoconstriction syndrome (RCVS) and transient global amnesia (TGA) can occur together. This case report highlights their co-occurrence and suggests a potential shared cause for these neurological conditions.
Area of Science:
- Neurology
- Neuroscience
Background:
- Reversible cerebral vasoconstriction syndrome (RCVS) and transient global amnesia (TGA) are distinct acute, self-limiting neurological conditions.
- Increasing case reports suggest a potential co-occurrence of RCVS and TGA, prompting investigation into shared pathophysiologies.
Approach:
- This study presents a case of a 55-year-old male experiencing thunderclap headaches and anterograde memory loss.
- Diagnostic imaging included MRI brain and CT angiogram, revealing hippocampal diffusion restriction consistent with TGA and later demonstrating RCVS.
- Treatment involved acetaminophen and verapamil, with complete resolution of symptoms.
Key Points:
- The patient presented with symptoms of both TGA and RCVS.
- Neuroimaging confirmed the diagnoses, showing characteristic findings for both conditions.
- Complete clinical recovery was achieved with appropriate medical management.
Conclusions:
- The co-occurrence of RCVS and TGA in this patient, alongside similar reported cases, suggests a possible common pathophysiological link.
- Further research is warranted to elucidate the relationship and underlying mechanisms connecting these two neurological syndromes.
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