Related Experiment Video
Updated: Aug 15, 2025
07:15
Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
11.6K
Exploring the correlation between COVID 19 and periodontal disease
Fatema Sayeed1,2, Keya Sircar3
1Faculty of Dentistry, Jamia Millia Islamia, Jamia Nagar, New Delhi.
Journal of Oral and Maxillofacial Pathology : JOMFP
|January 2, 2023
Summary
Periodontal disease, an oral infection, is linked to severe COVID-19 outcomes. Further research into this connection may identify new treatments and screening methods for high-risk patients.
Area of Science:
- Oral health
- Infectious diseases
- Public health
Background:
- The COVID-19 pandemic highlighted various factors influencing disease severity.
- An observed association exists between periodontal disease and severe COVID-19.
- Understanding this link is crucial for public health strategies.
Purpose of the Study:
- To explore hypotheses connecting periodontal disease and COVID-19 severity.
- To elucidate the interrelationship between oral health and respiratory viral infections.
- To identify potential therapeutic targets and screening opportunities.
Main Methods:
- Literature review of studies investigating periodontal disease and COVID-19.
- Analysis of proposed biological mechanisms linking the two conditions.
- Synthesis of current evidence on the association.
Main Results:
- Periodontal disease may exacerbate COVID-19 by increasing systemic inflammation.
- Viral load and host immune response are potentially modulated by oral bacteria.
- Specific inflammatory pathways are implicated in both conditions.
Conclusions:
- The association between periodontal disease and severe COVID-19 warrants further investigation.
- Targeted research can validate screening for high-risk populations.
- Identifying shared mechanisms may reveal novel therapeutic strategies for both conditions.
Related Concept Videos
01:15Teeth
558
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
558
01:26Factors Affecting the Risk of Infection
12.1K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
12.1K
01:27Correlation and Causation
37.9K
Statistical tests can calculate whether there is a relationship, or correlation, between independent and dependent variables. An indirect relationship of the variables signifies a correlation, while a direct relationship shows causation. If it is determined that no connection exists between the variables, then the correlation is a coincidence.
Correlation versus Causation
If the dependent variable increases or decreases when the independent variable increases, there is a positive or negative...
Correlation versus Causation
If the dependent variable increases or decreases when the independent variable increases, there is a positive or negative...
37.9K
01:26Assessment of the Mouth
326
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
326
01:21Tooth Anatomy
829
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
829
01:20COPD: Pathogenesis and Clinical Features
427
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
427