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Epidemiology, Pathophysiology, and Management of Coronary Artery Disease in the Elderly

Kahtan Fadah1, Aimee Hechanova1, Debabrata Mukherjee2

  • 1Department of Internal Medicine, Texas Tech University Health Sciences Center, El Paso, Texas.

The International Journal of Angiology : Official Publication of the International College of Angiology, Inc
|January 2, 2023
PubMed

Insights

Elderly patients over 75 are at high risk for coronary artery disease (CAD). This review covers CAD

Area of Science:

  • Cardiology
  • Geriatric Medicine
  • Atherosclerosis Research

Background:

  • Elderly patients (≥75 years) face heightened susceptibility to coronary artery disease (CAD).
  • CAD significantly contributes to mortality and morbidity in the aging population.
  • Research in this demographic is limited due to frailty and treatment preferences.

Purpose of the Study:

  • To provide a comprehensive overview of coronary artery disease (CAD) in older adults.
  • To examine the epidemiology, pathophysiology, and management strategies for CAD in the elderly.
  • To highlight the challenges and importance of studying CAD in this high-risk group.

Main Methods:

  • Review of existing epidemiological data on CAD in elderly populations.
  • Analysis of the pathophysiological mechanisms of atherosclerosis in older adults.
  • Synthesis of current management guidelines and treatment approaches for CAD in seniors.

Main Results:

  • Age is a critical nonmodifiable risk factor for atherosclerosis and adverse CAD outcomes.
  • Older adults present unique challenges in CAD diagnosis and treatment.
  • Evidence-based management is crucial for improving outcomes in elderly CAD patients.

Conclusions:

  • Coronary artery disease (CAD) poses a significant threat to the health of older adults.
  • Understanding the specific epidemiology and pathophysiology is key to effective management.
  • Further research is needed to optimize CAD care for the aging population.

Keywords:
agingatherosclerosiscoronary artery diseaseelderlyfrailtyrevascularization

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