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Updated: Aug 8, 2026

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Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis
Published on: July 4, 2007
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Case report: Pain in anti-DPPX encephalitis
Tale L Bjerknes1, Ole Martin Steihaug2, Mette Haugen1
1Neuro-SysMed, Department of Neurology, Haukeland University Hospital, Bergen, Norway.
Frontiers in Neurology
|January 2, 2023
Summary
Dipeptidyl-peptidase-like protein 6 (DPPX) encephalitis is rare but can present with severe pain. Early diagnosis and immunosuppressive treatment lead to favorable outcomes in patients with DPPX-associated autoimmune encephalitis.
Area of Science:
- Neuroimmunology
- Neurology
Background:
- Autoimmune encephalitis targeting potassium channel subunit dipeptidyl-peptidase-like protein 6 (DPPX) is uncommon.
- While typically presenting with weight loss, central nervous system hyperexcitability, and cognitive issues, DPPX encephalitis exhibits a heterogeneous clinical spectrum.
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