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Updated: Aug 15, 2025

Electroencephalography Network Indices as Biomarkers of Upper Limb Impairment in Chronic Stroke
Published on: July 14, 2023
Ischemic stroke cases presenting with hand weakness mimicking peripheral neuropathy.
Gulin Morkavuk1, Kübra Işık1, Zeki Odabaşı2
1Department of Neurology, Ufuk University Faculty of Medicine, Ankara, Türkiye.
Isolated upper extremity weakness, often misdiagnosed as peripheral neuropathy, can be a rare sign of ischemic stroke. Early cranial magnetic resonance imaging is crucial for accurate diagnosis of pure motor monoparesis.
Area of Science:
- Neurology
- Neuroscience
- Stroke Medicine
Background:
- Pure motor monoparesis affecting a single extremity is an uncommon presentation of ischemic stroke.
- This condition is frequently misdiagnosed, often initially mistaken for peripheral neuropathy.
Observation:
- Three cases of isolated upper extremity monoparesis, specifically left hand weakness, are presented.
- Initial electromyography in other centers suggested peripheral neuropathy.
- Repeat electromyography in our clinic yielded normal results, prompting further investigation.
Findings:
- Cranial magnetic resonance imaging revealed ischemic infarctions correlating with the patients' symptoms.
- The study highlights the diagnostic challenge of stroke presenting as isolated monoparesis.
Implications:
- Clinicians should consider pure motor monoparesis as a potential stroke symptom, even with isolated limb weakness.
- Prompt neuroradiological imaging is essential for accurate and timely diagnosis of stroke presenting with isolated monoparesis.
- This underscores the importance of considering central nervous system causes for peripheral-like symptoms.
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