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[Pituitary apoplexy]
Problemy Endokrinologii
|July 1, 1987
Summary
Pituitary apoplexy, a rare complication of pituitary adenomas, occurred in 10 patients over 5 years, most frequently in those with Nelson's syndrome. Early symptoms include headaches, nausea, and vomiting, but diagnosis is often delayed.
Area of Science:
- Endocrinology
- Neuro-oncology
- Ophthalmology
Context:
- Pituitary apoplexy is a rare but serious complication of pituitary adenomas.
- This study reviewed 10 cases of pituitary apoplexy treated over five years at a specialized institute.
Purpose:
- To analyze the incidence, clinical presentation, and diagnostic challenges of pituitary apoplexy.
- To highlight the association between pituitary apoplexy and Nelson's syndrome.
Summary:
- Pituitary apoplexy represented 5.06% of pituitary adenoma cases treated.
- Nelson's syndrome showed the highest frequency of pituitary apoplexy, with it being the initial presentation in 50% of these cases.
- Common symptoms included headaches, nausea, vomiting, ptosis, and ophthalmoplegia. A significant number of patients (70%) were initially misdiagnosed and treated in non-endocrine departments.
Impact:
- Highlights the importance of considering pituitary apoplexy in patients with pituitary adenomas, especially those with Nelson's syndrome.
- Emphasizes the need for improved diagnostic accuracy and timely referral to endocrinology services to prevent delayed treatment and potential complications.