Related Experiment Video

Updated: Aug 15, 2025

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
09:52

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis

Published on: March 9, 2018

10.6K

Burden of Serious Fungal Infections in India

Animesh Ray1, Adarsh Aayilliath K1, Sayantan Banerjee2

  • 1Department of Medicine, AIIMS, New Delhi, India.

Open Forum Infectious Diseases
|January 2, 2023
PubMed
Abstract

Insights

Fungal infections affect over 4% of India's population, with millions experiencing serious conditions like candidiasis and aspergillosis. This high burden of fungal disease in India is often overlooked in clinical settings.

Area of Science:

  • Medical Mycology
  • Infectious Diseases Epidemiology
  • Public Health

Background:

  • Fungal infections are common in India, yet their exact incidence and prevalence remain largely unknown.
  • Understanding the burden of fungal diseases is crucial for public health planning and resource allocation.

Purpose of the Study:

  • To determine the frequency and burden of various fungal infections across India.
  • To provide updated epidemiological data on serious fungal diseases in the Indian population.

Main Methods:

  • A systematic literature review was performed across PubMed, Embase, and Web of Science databases.
  • Deterministic modeling was employed to estimate annual incidence and prevalence rates for key fungal infections.
  • Data from over 434 relevant studies were analyzed to quantify the fungal disease burden.

Main Results:

  • An estimated 4.1% of India's population (over 57 million people) suffer from serious fungal diseases.
  • High prevalence rates were found for recurrent vulvovaginal candidiasis (24.3 million) and tinea capitis (25 million).
  • Significant annual incidence was noted for fungal keratitis (1,017,100), mucormycosis (195,000), and invasive aspergillosis (250,900).

Conclusions:

  • India faces a substantial and underestimated burden of fungal diseases.
  • The findings highlight the need for increased clinical awareness and improved management strategies for fungal infections in India.
Keywords:
AspergillusCandidaCryptococcusPneumocystishistoplasmosismycetomasporotrichosistinea capitis

More Related Videos

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract07:42

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract

Published on: July 1, 2020

5.4K
Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis08:48

Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis

Published on: March 19, 2019

7.0K

Related Concept Videos

Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
73
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
297
Fungal Group Zygomycota01:29

Fungal Group Zygomycota

Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
75
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
225
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
409
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
186