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Related Concept Videos

Pulse rhythm01:30

Pulse rhythm

891
Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
891
Dysrhythmias V: Evaluating Dysrhythmias01:30

Dysrhythmias V: Evaluating Dysrhythmias

45
Dysrhythmias, also known as arrhythmias, are disturbances in the heart's rhythm that range from benign to life-threatening. A thorough evaluation is crucial for appropriate management and involves a comprehensive medical history, physical examination, and various diagnostic tests.Medical HistorySymptoms: Collect detailed information on palpitations, dizziness, syncope, chest pain, and fatigue. Note their onset, frequency, and triggers.Previous Cardiac Issues: Document any history of heart...
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Dysrhythmias VI: Management of Dysrhythmias01:25

Dysrhythmias VI: Management of Dysrhythmias

28
Dysrhythmia management involves a multifaceted approach, incorporating pharmacological treatments, medical procedures, surgical interventions, lifestyle modifications, and patient education.Pharmacological ManagementAntiarrhythmic Drugs:Class I (Sodium Channel Blockers): This class includes quinidine and procainamide, which reduce the speed of impulse conduction in the heart, stabilize the cardiac membrane, and control arrhythmias. Quinidine and procainamide are Class IA agents that prolong the...
28
Dysrhythmias VII: Nursing Management of Dysrhythmias01:25

Dysrhythmias VII: Nursing Management of Dysrhythmias

22
Nursing management of dysrhythmias involves the following:AssessmentSubjective Assessment:The initial step involves gathering patient-reported symptoms such as dizziness, palpitations, and chest discomfort. It is crucial to collect a detailed history, including previous heart conditions, current medication use, and lifestyle factors like caffeine and alcohol consumption.Objective Assessment:This involves observing clinical signs such as jugular venous distention, cool and pale skin, and...
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Related Experiment Video

Updated: Aug 15, 2025

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
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Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

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Rate or Rhythm Control in CRT (RHYTHMIC): Study rationale and protocol.

Mark K Elliott1,2, Felicity de Vere1,2, Vishal S Mehta1,2

  • 1School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.

Heart Rhythm O2
|January 2, 2023
PubMed
Summary
This summary is machine-generated.

Atrial fibrillation (AF) negatively impacts heart failure patients receiving cardiac resynchronization therapy (CRT). This study compares AV node ablation and AF ablation to improve outcomes in these patients.

Keywords:
Atrial fibrillationAtrial fibrillation ablationAtrioventricular node ablationAtrioventricular synchronyBiventricular pacing percentageCardiac resynchronization therapy

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Area of Science:

  • Cardiology
  • Electrophysiology
  • Heart Failure Management

Background:

  • Atrial fibrillation (AF) complicates cardiac resynchronization therapy (CRT) by impairing biventricular pacing and atrioventricular (AV) synchrony.
  • AV node ablation is known to improve CRT outcomes, but AF ablation's potential benefits in restoring sinus rhythm are less understood.

Purpose of the Study:

  • To compare the efficacy of AV node ablation versus AF ablation in patients with CRT and suboptimal biventricular pacing.
  • To assess the impact of each ablation strategy on echocardiographic and symptomatic outcomes.

Main Methods:

  • The RHYTHMIC trial is a multicenter prospective randomized controlled trial involving 70 patients with CRT and AF-induced suboptimal biventricular pacing.
  • Patients are randomized 1:1 to undergo either AV node ablation or AF ablation.
  • Primary endpoint is the change in left ventricular ejection fraction assessed by transthoracic echocardiography (TTE) at 6 months.

Main Results:

  • Baseline assessments include TTE, ECG, 6-minute walk test, and symptom questionnaires.
  • Follow-up includes TTE and ECG at 1 week and comprehensive reassessment at 6 months.

Conclusions:

  • This is the first randomized controlled trial directly comparing AV node ablation and AF ablation in CRT patients with AF.
  • Findings will offer crucial insights into managing this complex patient population.