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Updated: Aug 15, 2025

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A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death
Published on: June 6, 2025
230
Redo heart transplant without allogeneic blood transfusion
Quynh Nguyen1, Vinod Manikala2,3, Danika Vautour3,4
1Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada.
Indian Journal of Thoracic and Cardiovascular Surgery
|January 2, 2023
Summary
This case study shows a successful heart transplant without blood transfusions, using blood conservation strategies. This approach can reduce risks and costs associated with allogeneic blood transfusions in cardiac surgery.
Area of Science:
- Cardiovascular Surgery
- Transplantation Medicine
- Anesthesiology
Background:
- Allogeneic blood transfusions in cardiac surgery correlate with adverse outcomes, including higher morbidity, mortality, and healthcare expenses.
- Minimizing allogeneic blood use is a critical goal in complex cardiac procedures.
Observation:
- A patient underwent a third-time redo sternotomy and second-time redo heart transplantation.
- This complex procedure was performed without the need for allogeneic blood transfusion.
Findings:
- The successful transfusion-free outcome was attributed to the implementation of multiple perioperative blood conservation strategies.
- These strategies effectively managed blood loss and minimized the requirement for donor blood.
Implications:
- This case demonstrates the feasibility of transfusion-free cardiac transplantation, even in high-risk, reoperative scenarios.
- Adoption of comprehensive blood conservation protocols may improve patient outcomes and reduce healthcare costs in cardiac surgery.
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