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Updated: Aug 15, 2025

Vascularized Composite Hand Allograft Procurement and Preparation for Distal and Proximal Forearm Allotransplantation: A Stepwise Approach
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Changes in Primary Somatosensory Cortex Following Allogeneic Hand Transplantation or Autogenic Hand Replantation

B A Philip1,2, K F Valyear1,3, C M Cirstea4

  • 1University of Missouri, Department of Psychological Sciences, Columbia, MO, USA.

Frontiers in Neuroimaging
|January 2, 2023
PubMed
Summary

Hand restoration surgery, including transplantation and replantation, shows primary somatosensory cortex (S1) function within typical ranges. However, individual variability and low-amplitude responses suggest significant post-deafferentation brain plasticity.

Keywords:
amputationcortical reorganizationdeafferentationhand replantationhand transplantationreplantationsomatosensory cortextactile sensation

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