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Updated: Aug 15, 2025

Gene Digital Circuits Based on CRISPR-Cas Systems and Anti-CRISPR Proteins
Published on: October 18, 2022
Generation of all randomizations using circuits
Elena Pesce1, Fabio Rapallo2, Eva Riccomagno3
1Swiss Re Institute, Swiss Re Management Ltd, Mythenquai 50/60, 8022 Zurich, Switzerland.
Abstract:
After a rich history in medicine, randomized control trials (RCTs), both simple and complex, are in increasing use in other areas, such as web-based A/B testing and planning and design of decisions. A main objective of RCTs is to be able to measure parameters, and contrasts in particular, while guarding against biases from hidden confounders. After careful definitions of classical entities such as contrasts, an algebraic method based on circuits is introduced which gives a wide choice of randomization schemes.
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