Related Experiment Video
Updated: Aug 15, 2025

Monitoring Lung Function with Electrical Impedance Tomography in the Intensive Care Unit
Published on: September 6, 2024
The influence of reference electrode in electrical impedance tomography
Zhimin Lin1, Weixiang Huang1, Zhijun Gao2
1State Key Lab of Respiratory Diseases, Guangzhou Institute of Respiratory Health, Guangzhou Medical University, The First Affiliated Hospital of Guangzhou Medical University, Department of Critical Care Medicine, Guangzhou, China.
Ensure proper contact for reference electrodes in electrical impedance tomography (EIT) systems. Disconnecting the reference electrode significantly impacts EIT data quality and image reconstruction in most subjects.
Area of Science:
- Biomedical Engineering
- Medical Imaging
- Physiology
Background:
- Electrical impedance tomography (EIT) devices often include reference electrodes.
- High contact impedance for reference electrodes is a practical challenge.
- The impact of poor reference electrode contact on EIT data quality is not well understood.
Purpose of the Study:
- To investigate the influence of the reference electrode on EIT image reconstruction.
- To assess the impact of reference electrode connectivity on EIT data quality.
Main Methods:
- Thirty healthy volunteers underwent EIT measurements during spontaneous breathing.
- Three scenarios were tested: normal measurement, reference electrode disconnected without recalibration, and disconnected with recalibration.
- EIT parameters for spatial and temporal ventilation were calculated and compared using a deviation score.
Main Results:
- Significant differences in EIT parameters were observed when the reference electrode was disconnected (p < 0.01).
- The average deviation score was 4.5 ± 3.5 without recalibration and 6.1 ± 3.1 with recalibration.
- Only a small subset of subjects (4/30 without recalibration, 2/30 with recalibration) showed minimal deviation.
Conclusions:
- Proper contact and functionality of the reference electrode are crucial for EIT systems.
- EIT data quality is significantly affected by reference electrode status in most individuals.
- Maintaining reference electrode integrity is essential for reliable EIT image reconstruction.
More Related Videos
09:36In Situ Lithiated Reference Electrode: Four Electrode Design for In-operando Impedance Spectroscopy
Published on: September 12, 2018
10:51Fabrication and Validation of an Organ-on-chip System with Integrated Electrodes to Directly Quantify Transendothelial Electrical Resistance
Published on: September 26, 2017