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Voice Outcomes From Direct Vocal Fold Testosterone Injections, a Case Report
Andrew M Vahabzadeh-Hagh1, Erin Walsh1, Vala Hamidi2
1Department of Otolaryngology, Head and Neck Surgery, University of California, La Jolla, California, USA.
The Laryngoscope
|January 3, 2023
Summary
Targeted vocal fold testosterone injections successfully masculinized the voices of transgender men. This safe and effective treatment yielded durable results within weeks.
Area of Science:
- Otolaryngology
- Endocrinology
- Gender-affirming care
Background:
- Voice changes are a key aspect of gender transition for transgender men.
- Hormone therapy with testosterone is standard but can lead to unpredictable vocal outcomes.
- Surgical interventions for voice feminization exist, but masculinization options are limited.
Observation:
- The study presents the first documented case of targeted vocal fold testosterone injection.
- Two transgender male patients received the novel injection treatment.
- Vocal fold changes were monitored for voice masculinization efficacy.
Findings:
- Successful voice masculinization was achieved in both patients.
- Positive vocal outcomes were observed within 2-3 weeks post-injection.
- The treatment demonstrated a durable effect with no reported side effects.
Implications:
- This targeted injection offers a new, potentially more predictable method for voice masculinization in transgender men.
- It may provide an alternative or adjunct to systemic hormone therapy for vocal effects.
- Further research can explore wider application and long-term outcomes of this technique.
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