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Acupuncture for migraine prophylaxis: A protocol for systematic review and Bayesian network meta-analysis
Wenyan Zhu1, Yiwen Cai, Yijun Zhan
1Department of Acupuncture, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Medicine
|January 3, 2023
Summary
This study will compare various acupuncture therapies for migraine prevention. The goal is to identify the most effective and safe treatments for reducing migraine frequency and intensity.
Area of Science:
- Neurology
- Integrative Medicine
- Evidence-Based Medicine
Background:
- Migraine affects 1 billion people globally, causing significant health and social burdens.
- Acupuncture is a recognized and effective therapy for migraine prophylaxis, supported by clinical evidence and expert recommendations.
Purpose of the Study:
- To conduct a Bayesian network meta-analysis comparing the efficacy of diverse acupuncture therapies for migraine prophylaxis.
- To provide evidence-based guidance for clinicians in selecting optimal and safe migraine prevention strategies.
Main Methods:
- Systematic literature search across multiple databases (PubMed, Embase, Cochrane, etc.) for randomized controlled trials up to July 1, 2022.
- Independent study selection, data extraction, and risk of bias assessment by two reviewers.
- Pairwise and Bayesian network meta-analyses using Review Manager 5.3 and R software packages ('gemtc', 'rjags').
Main Results:
- The analysis will compare the effectiveness of different acupuncture modalities in preventing migraine episodes.
- Outcomes include reduction in migraine frequency, duration, headache intensity, and assessment of adverse events.
Conclusions:
- This network meta-analysis aims to establish a hierarchy of evidence for various acupuncture therapies in migraine prophylaxis.
- Findings will support clinicians in developing personalized and effective treatment plans for migraine patients.
