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Updated: Sep 14, 2026

Author Spotlight: Using Motor Imagery Brain-Computer Interface to Improve Motor and Cognitive Function in Stroke Patients
Published on: September 1, 2023
Case report of anosognosia for hemiplegia: A fMRI study
Caterina Formica1, Simona De Salvo, Francesco Corallo
1IRCCS Centro Neurolesi "Bonino Pulejo", Messina, Italy.
Objective:
The aim of this study is to verify the functional activation in a patient with anosognosia for hemiplegia following left brain lesions.
Methods:
We report a case of a 53-year-old right-handed female patient. She came to our rehabilitative unit with a diagnosis of an ischemic major stroke in the left internal carotid artery and important hemiplegia to the right side. She underwent functional magnetic resonance imaging (fMRI), during which she performed a motor imagery task.
Results:
The fMRI assessment showed an ischemic lesion in the frontotemporal and insular left areas. In the fMRI experiment, we revealed activation of the residual neural patterns of both hemispheres.
Conclusion:
We underlined an interest in the compensation mechanism that involved neural networks near brain lesions and some areas of the contro-lesional hemisphere, suggesting that the synaptic plasticity permitted an intra and inter-hemispheric reorganization of the cerebral system.

