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Updated: Aug 15, 2025

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
Published on: February 2, 2024
Anaerobiospirillum succiniciproducens prosthetic joint infection
George V Youssef1, Papia Kar2, Subhashis Mitra1
1Division of Infectious Diseases, Department of Internal Medicine, College of Human Medicine, Michigan State University, East Lansing, MI, USA.
Abstract:
Anaerobiospirillum succiniciproducens is a rare anaerobic pathogen that is implicated in sporadic cases of bacteremia and diarrhea, usually in immunocompromised patients. We describe a case of prosthetic joint infection in a 71 year old male who presented with right hip pain. Anaerobic cultures from tissue specimen grew a spiral-shaped gram-negative rod, identified as A. succiniciproducens by 16S rRNA gene sequencing. The patient was treated successfully with IV cefoxitin for 6 weeks. To our knowledge this is only the third reported case of prosthetic joint infection due to A. succiniciproducens.
Insights
Anaerobiospirillum succiniciproducens, a rare anaerobic pathogen, caused a prosthetic joint infection in an immunocompromised patient. This is only the third reported case, successfully treated with IV cefoxitin.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Orthopedic Surgery
Background:
- Anaerobiospirillum succiniciproducens is a rare anaerobic bacterium.
- It is typically associated with sporadic cases of bacteremia and diarrhea, particularly in immunocompromised individuals.
- Prosthetic joint infections (PJIs) are serious complications requiring prompt diagnosis and treatment.
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