Modelling binary data from a three-period cross-over trial
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1Mathematical Institute, The University, Canterbury, Kent, U.K.
Statistics in Medicine
|July 1, 1987
Abstract:
A new method of analysing binary data from a three-treatment, three-period cross-over trial is described. This method is based on a log-linear model and mirrors the analysis of continuous data. It is an extension of the method we introduced recently for the analysis of binary data from a two-treatment, two-period cross-over trial. We illustrate our method using data from a trial which compared two analgesics and a placebo for the relief of primary dysmenorrhea.