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Updated: Aug 15, 2025

Fabrication of Engineered Vascular Flaps Using 3D Printing Technologies
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Emerging 3D bioprinting applications in plastic surgery.

Pu Yang1, Yikun Ju1, Yue Hu2

  • 1Department of Plastic and Aesthetic (Burn) Surgery, The Second Xiangya Hospital, Central South University, Changsha, 410011, People's Republic of China.

Biomaterials Research
|January 3, 2023
PubMed
Summary

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Three-dimensional (3D) bioprinting offers customized implants for plastic surgery, reducing complications. This review explores 3D bioprinting

Area of Science:

  • Regenerative Medicine
  • Biotechnology
  • Plastic Surgery

Background:

  • Plastic surgery reconstructs defects using surgical methods or tissue transplantation.
  • Three-dimensional (3D) bioprinting allows precise, patient-specific implant customization.
  • This technology aims to mitigate adverse reactions and complications associated with traditional approaches.

Purpose of the Study:

  • To review recent advancements in 3D bioprinting applications within plastic surgery.
  • To elucidate the principles, materials, and technologies of 3D bioprinting.
  • To examine clinical viability, challenges, and future prospects.

Main Methods:

  • Review of current research on 3D bioprinting in plastic surgery.
  • Introduction to 3D bioprinting processes and fundamental principles.
Keywords:
3D bioprintingBiomaterialsPlastic surgeryTissue engineeringTissue regeneration

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  • Analysis of bioprinting materials and the concept of 4D bioprinting.

    • Main Results:

    • 3D bioprinting enables customized preoperative implant design.
    • Exploration of various bioprinting technologies, materials, and their advantages/disadvantages.
    • Discussion of dynamic 3D bioprinting (4D bioprinting) through material combinations.

    Conclusions:

    • 3D bioprinting presents significant potential for advancing plastic surgery.
    • Understanding materials and technologies is crucial for successful clinical application.
    • Further research is needed to overcome challenges and realize the full prospects of 3D bioprinting in this field.