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Updated: Aug 15, 2025

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Isolation of Neonatal Extrahepatic Cholangiocytes
Published on: June 5, 2014
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Liver Abscess in a Cyanotic Newborn.
Bengisu Guner Yilmaz1,2, Serdar Beken3, Eda Albayrak3
1Department of Paediatrics, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.
Summary
A rare liver abscess complication occurred in a neonate with congenital heart disease following umbilical venous catheterization. Prompt diagnosis and drainage led to complete recovery.
Area of Science:
- Neonatal Medicine
- Pediatric Surgery
Background:
- Umbilical venous catheterization (UVC) is a common neonatal intensive care unit (NICU) procedure.
- Potential complications include thrombus, thromboembolism, vessel perforation, hemorrhage, and bloodstream infections.
Observation:
- A male infant with cyanotic congenital heart disease developed abdominal distension and clinical deterioration on day seven post-UVC insertion.
- Abdominal ultrasonography revealed a hepatic abscess.
- The infant's condition worsened despite UVC repositioning.
Findings:
- A pyogenic liver abscess, a rare but serious complication, was diagnosed.
- US-guided percutaneous drainage and Staphylococcus-targeted antibiotics were administered.
- Complete resolution of the hepatic abscess was observed within three weeks.
Implications:
- Clinical deterioration and gastrointestinal symptoms in neonates with UVC, especially those with cyanotic heart disease, warrant suspicion for liver abscess.
- Early diagnosis and intervention are crucial for managing this life-threatening complication.
- This case highlights the importance of vigilant monitoring for rare UVC complications.
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