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Common pregnancy complications and polyphenols intake: an overview
Iohanna Deckmann1, Júlio Santos-Terra1, Fátima Martel2,3
1Department of Biochemistry, Institute of Basic Health Sciences, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
Critical Reviews in Food Science and Nutrition
|January 4, 2023
Summary
Maternal polyphenol intake shows protective effects against preeclampsia, gestational diabetes, and fetal growth restriction. This review synthesizes evidence from human, animal, and in vitro studies to guide future research on these beneficial compounds during pregnancy.
Area of Science:
- Obstetrics and Gynecology
- Nutritional Science
- Pharmacology
Background:
- Pregnancy involves significant physiological changes to support fetal development.
- Maternal dietary supplementation is crucial for adequate fetal nutrition.
- Emerging research highlights the benefits of polyphenol intake during pregnancy.
Purpose of the Study:
- To review the effects of various polyphenols on common pregnancy-associated complications.
- To critically analyze existing literature on polyphenol supplementation in pregnancy.
- To summarize evidence for guiding future research on polyphenols in pregnancy.
Main Methods:
- Comprehensive literature review of human, animal, and in vitro studies.
- Analysis of outcomes related to preeclampsia, gestational diabetes, and fetal growth restriction.
- Evaluation of different polyphenols, extracts, and juices.
Main Results:
- Polyphenol ingestion demonstrates a protective effect against preeclampsia.
- Evidence suggests benefits of polyphenols in managing gestational diabetes.
- Polyphenols show a positive impact on preventing fetal growth restriction.
Conclusions:
- Polyphenols offer protective benefits for key pregnancy complications.
- Consistent evidence supports the role of polyphenols in improving maternal and fetal outcomes.
- This review provides a foundation for designing future clinical trials on polyphenol interventions.
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