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Drug Therapy

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
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When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...

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Related Experiment Video

Updated: Aug 15, 2025

Diagonal Method to Measure Synergy Among Any Number of Drugs

Diagonal Method to Measure Synergy Among Any Number of Drugs

Published on: June 21, 2018

[Choosing Wisely in Patients with Polypharmacy].

Stefan Neuner-Jehle¹

¹Institut für Hausarztmedizin, Universität und Universitätsspital Zürich, Zürich, Schweiz.

|January 4, 2023

Summary

Deprescribing, or reducing medications, is vital for patient well-being. A stepwise approach involving shared decision-making and careful drug evaluation ensures safe and effective medication management for patients with polypharmacy.

Keywords:

Choosing Wisely Deprescribing Patientenwerte Polypharmacie Polypharmacy Polypharmazie Shared Decision Making deprescribing décision commune patient values valeurs des patients

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Area of Science:

Geriatrics
Pharmacology
Patient Safety

Context:

Polypharmacy and potentially inappropriate medication use negatively impact patient health outcomes.
Deprescribing is essential for improving patient well-being and managing complex medication regimens.

Purpose:

To outline a successful stepwise approach for deprescribing in patients with polypharmacy.
To emphasize the importance of shared decision-making and individualized medication review.

Summary:

The approach involves patient medication reconciliation, shared decision-making, and a thorough evaluation of each drug's indication, benefit-harm balance, side effects, and dosage.
Prioritizing patient values, preferences, and goals is key to deciding on deprescribing, followed by monitoring and follow-up.

Impact:

Implementing this structured deprescribing strategy can lead to improved patient outcomes and enhanced quality of life.
Deprescribing is as critical as medication prescribing for maintaining patient health and well-being.