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[Expert consensus on diagnosis and treatment of recurrent implantation failure]
Abstract:
Recurrent implantation failure (RIF) is a challenging clinical problem. Although in vitro fertilization-embryo transfer technology has made remarkable advances, RIF remains a significant obstacle to achieving a successful pregnancy. A unified criterion of diagnosis and treatment for RIF has yet to be created. The etiology of RIF is complicated, including maternal, male, and embryonic factors. Maternal factors include dysimmunity, prethrombotic state, poor endometrial receptivity, infection, anatomical abnormalities, and endocrine disorders. The complexity and diversity of etiologies of RIF require clinicians to individualize the strategy of diagnosis and treatment for RIF patients. This consensus will provide the most relevant evidence to date for the examination, evaluation, and management of RIF, provide a reference for clinicians to make decisions, and standardize the diagnosis and treatment of RIF.
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