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Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although...
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When the cancer is gone but fertility is uncertain: the urgent need for predictive tools in oncofertility.

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Updated: Aug 15, 2025

Fertility Preservation in Patients with Severe Ovarian Dysfunction
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[Methods for fertility preservation].

Kenny Rodriguez-Wallberg1

  • 1professor, överläkare, Reproduktionsmedicin, Karolins-ka universitetssjukhuset, Stockholm.

Lakartidningen
|January 4, 2023
PubMed
Summary

Fertility preservation methods like sperm and egg cryopreservation are available for medical reasons. Studies in Sweden show these procedures are safe for women with breast cancer.

Area of Science:

  • Reproductive Medicine
  • Oncology
  • Public Health

Context:

  • Fertility preservation services, including cryopreservation of gametes and gonadal tissue, are accessible at specialized centers.
  • In Sweden, these services are integrated into publicly funded healthcare, primarily for medically indicated cases.
  • Key patient groups include those with cancer, benign diseases, gender dysphoria, and genetic conditions necessitating fertility preservation.

Purpose:

  • To evaluate the long-term safety and efficacy of fertility preservation techniques.
  • To assess the safety of cryopreservation procedures specifically in cancer patients, particularly women with breast cancer.
  • To leverage Sweden's population-based healthcare registers for robust scientific research.

Summary:

  • Established cryopreservation methods for sperm, eggs, embryos, and gonadal tissue are widely available.

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  • Swedish healthcare offers fertility preservation for medically indicated reasons, with cancer patients forming the largest cohort.
  • Research utilizing Swedish health registers indicates the safety of these procedures for women diagnosed with breast cancer.
  • Impact:

    • Provides evidence supporting the safety of fertility preservation for oncological patients.
    • Informs clinical practice and patient counseling regarding fertility preservation options.
    • Highlights the value of national health registries in long-term safety research for medical procedures.