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The Y Chromosome Determines Maleness02:19

The Y Chromosome Determines Maleness

6.7K
The Y chromosome is a sex chromosome found in several vertebrates and mammals, including humans. In addition to 22 pairs of autosomes, the human males have one X chromosome and one Y chromosome. In these organisms, the presence or absence of the Y chromosome determines the development of male traits.
Evolution
Around 300 million years ago, the two sex chromosomes diverged from two identical autosomal chromosomes. Over time, the Y chromosome has lost most of its genes, shrinking in size....
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X and Y Chromosomes02:32

X and Y Chromosomes

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Among mammals, the gender of an organism is determined by the sex chromosomes. Humans have two sex chromosomes, X and Y. Every human diploid cell has 22 pairs of autosomes and one pair of sex chromosomes. A human female has two X chromosomes, while a male has one X chromosome and one Y chromosome.
The germline cells such as egg and sperm cells carry only half the number of chromosomes, i.e., 22 autosomes and one sex chromosome. All eggs have an X chromosome, while sperm cells can carry an X or...
26.5K
Pedigree Analysis01:35

Pedigree Analysis

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Overview
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The Ratio of X Chromosome to Autosomes02:45

The Ratio of X Chromosome to Autosomes

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In most organisms, sex is determined by the ratio of X and Y chromosomes. However, in some organisms, such as Drosophila and C.elegans, sex is determined by the ratio of the number of X chromosomes to the number of sets of autosomes. The Y chromosome in Drosophila is active but does not determine sex. It contains genes responsible for the production of sperms in adult flies.  
Normal male Drosophila has a ratio of one X chromosome to two sets of autosomes. In contrast, normal female...
8.7K
Sex-linked Disorders01:43

Sex-linked Disorders

102.6K
Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
102.6K
Dosage Compensation02:50

Dosage Compensation

6.3K
In animals, gender is determined by the number and type of sex chromosome. For example, human females have two X chromosomes, and males have one X and one Y chromosome, whereas C.elegans with one X chromosome is a male, and the one with two X chromosomes is a hermaphrodite.
In addition to sexual development, the X chromosome has genes involved in autosomal functions such as brain development and the immune system. Therefore, males and females with  distinct numbers of X chromosomes will...
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Related Experiment Video

Updated: Aug 15, 2025

Exploring X Chromosomal Aberrations in Ovarian Cells by Using Fluorescence In Situ Hybridization
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Exploring X Chromosomal Aberrations in Ovarian Cells by Using Fluorescence In Situ Hybridization

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How to manage without a Y chromosome

Manfred Schartl1, Dunja K Lamatsch2

  • 1Developmental Biochemistry, Biocenter, University of Wuerzburg, D-97074 Wuerzburg, Germany.

Proceedings of the National Academy of Sciences of the United States of America
|January 4, 2023
PubMed
Summary

No abstract available in PubMed .

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