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Updated: Aug 15, 2025
Synthesis of Stimuli-responsive Nanogels using Aqueous One-step Crosslinking and Co-nanopolymerization
Published on: January 24, 2025
Nanostructured multifunctional stimuli-responsive glycopolypeptide-based copolymers for biomedical applications.
Mahsa Sedighi1, Zahra Mahmoudi2, Alireza Ghasempour3
1Department of Pharmaceutics and Nanotechnology, School of Pharmacy, Birjand University of Medical Sciences, Birjand, Iran; Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran.
Glycopolypeptides, inspired by nature, form self-assembling nanostructures for advanced biomedical uses. These biopolymers show promise in drug delivery and regenerative medicine, though clinical translation requires further development.
Area of Science:
- Biochemistry and Materials Science
- Focus on novel biopolymers derived from natural resources.
- Exploration of glycopolypeptides in biomedical engineering.
Background:
- Glycopolypeptides are emerging biopolymers inspired by peptides and carbohydrates.
- They possess well-defined secondary structures with pendant glycosides.
- These characteristics enable self-assembly into diverse nanostructures.
Conclusions:
- Glycopolypeptides are versatile biopolymers with significant biomedical potential.
- Nanocarriers derived from glycopolypeptides show promise for targeted drug delivery.
- Further research is needed to overcome limitations in clinical translation.
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