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A Xanthan-Gum-Stabilized PEG-Conjugated Nanocurcumin Complex: Telescoping Synthesis for Enhanced Permeation Potential
Prem Pandey1, Supriya Chaturvedi2, Rutuja Gumathannavar1
1Symbiosis Center for Nanoscience and Nanotechnology (SCNN), Symbiosis International (Deemed University) (SIU) Lavale, Pune, 412115, Maharashtra, India.
Abstract:
We report a facile room temperature telescoping synthesis of a nanocurcumin complex with 17.5-fold permeation enhancement as determined by comparative in vitro permeation study with raw curcumin. The permeation results were further validated with in silico drug absorption prediction using ADMET predictors.
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