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Resistance to the effects of thyroid hormone in children
K R Rettig1, D T Sargeant, S F Kemp
1University of South Alabama, Mobile 36617.
Southern Medical Journal
|October 1, 1987
Abstract:
We have described three children with serum levels of TSH that are too high for the concomitant serum T4 level. Two of them meet the criteria for combined central and peripheral resistance to thyroid hormone. The third has long-standing central resistance to TSH suppression previously reported in congenital hypothyroidism. The recognition of this syndrome by physicians is important to avoid unnecessary and potentially dangerous treatment.