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SARS-CoV-2 Omicron Variant in Patients With Chronic Lymphocytic Leukemia: Case Series
Ibrahim Khamees1, Elrazi A Ali2, Lujain Malkawi3
1Internal Medicine, Hamad Medical Corporation, Doha, QAT.
Insights
The Omicron variant of severe acute respiratory syndrome-Coronavirus-2 (SARS-CoV-2) may cause mild illness in chronic lymphocytic leukemia (CLL) patients. This case series reports on three CLL patients infected with Omicron, detailing their outcomes.
Area of Science:
- Virology
- Hematology
- Infectious Diseases
Background:
- The COVID-19 pandemic, caused by SARS-CoV-2, has seen numerous viral strains emerge.
- The Omicron variant (B.1.1.529) is known for its transmissibility, but its impact on immunocompromised individuals, like those with CLL, remains unclear.
Abstract:
The Coronavirus disease 2019 (COVID-19) is considered the largest pandemic in modern history. Since the first case was reported in 2019, several mutations have affected the severe acute respiratory syndrome-Coronavirus-2 (SARS-CoV-2), resulting in the emergence of new strains. These strains vary significantly in severity and transmissibility. The Omicron (B.1.1.529) variant was reported to cause mild disease in those affected, but little is known about the effect of Omicron on patients with chronic lymphocytic leukemia (CLL). We are reporting a case series of three patients with CLL who experienced infection with the SARS-CoV-2 Omicron variant and their outcomes.
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