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Characteristics of patients with multiple arterial aneurysms

Daniel Körfer1, Philipp Erhart1, Markus Wortmann1,2

  • 1Department of Vascular and Endovascular Surgery, University Hospital Heidelberg, Germany.

VASA. Zeitschrift Fur Gefasskrankheiten
|January 5, 2023
PubMed

Insights

Patients with multiple arterial aneurysms (mult-AA) are diagnosed younger and show different aneurysm locations compared to those with single arterial aneurysms (sing-AAA). This study highlights key demographic and localization differences in aneurysm patients.

Area of Science:

  • Vascular Surgery
  • Aneurysm Research
  • Epidemiology

Background:

  • Arterial aneurysms present a significant vascular disease burden.
  • Understanding differences between single and multiple aneurysm presentations is crucial for patient management.

Purpose of the Study:

  • To compare patients with multiple arterial aneurysms (mult-AA) against those with single arterial aneurysms (sing-AAA).
  • To identify differences in age at diagnosis, sex distribution, and affected arterial sites.

Main Methods:

  • Retrospective cross-sectional observational study of 2189 patients diagnosed with arterial aneurysms.
  • Comparison of mult-AA (≥4 aneurysms) and sing-AAA groups based on age, sex, and aneurysm location.
  • Replication of the study at a comparable institution to validate findings.

Main Results:

  • Patients with mult-AA were younger at initial diagnosis (66.7±9.5 y) than sing-AAA (69.1±8.6 y).
  • A higher proportion of males were observed in the mult-AA group (96.5%) compared to sing-AAA (89.0%).
  • Aneurysm localization shifted from the abdominal aorta in sing-AAA to pelvic and leg arteries in mult-AA.

Conclusions:

  • Multiple arterial aneurysms are associated with a younger age at initial diagnosis.
  • Distinct differences in aneurysm localization exist between patients with single and multiple aneurysms.

Keywords:
Abdominal aortic aneurysmage of onsetiliac aneurysmthoracic aortic aneurysmvascular diseases

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