Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Exenterative surgery for locally advanced rectosigmoid cancers. Is it worthwhile?

M J Lopez1, W G Kraybill, R S Downey

  • 1Department of Surgery, Ellis Fischel State Cancer Center, Columbia, MO 65203.

Surgery
|October 1, 1987
PubMed
Summary

Total pelvic exenteration for rectosigmoid cancer offers a survival rate exceeding 40% at 5 years. This procedure, while having risks, shows decreasing mortality and acceptable morbidity in selected patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Carbon source-dependent activation of herbicide-mixture degradation in a synthetic microbial community enriched from black soil.

Journal of hazardous materials·2026
Same author

Microbial community in a soilless cultivation system with organic fertilization, biofertilizers and cover crop rotation.

The Science of the total environment·2025
Same author

Corrigendum to "Aqueous compost extracts with stabilized biofertilizing microbiota promote plant root growth and drought resilience" [Sci. Total Environ. 974 (2025) 179157].

The Science of the total environment·2025
Same author

Cataloging olive oil mill wastewater sludge based on toxicological profiles and functional microbial diversity.

The Science of the total environment·2025
Same author

Aqueous compost extracts with stabilized biofertilizing microbiota promote plant root growth and drought resilience.

The Science of the total environment·2025
Same author

Changes in social inequalities in excess body weight and body dissatisfaction among adolescents in Barcelona, Spain, 2016-2021.

Public health·2024

Area of Science:

  • Oncology
  • Surgical Oncology
  • Gastrointestinal Surgery

Background:

  • Rectosigmoid cancers present significant treatment challenges, particularly when locally advanced.
  • Total pelvic exenteration (TPE) is a radical surgical option for select cases.

Purpose of the Study:

  • To evaluate the outcomes of total pelvic exenteration for rectosigmoid cancer.
  • To assess the morbidity, mortality, and survival rates associated with TPE.

Main Methods:

  • Retrospective analysis of 24 patients who underwent TPE for rectosigmoid cancer over 30 years.
  • Review of clinicopathologic data, including staging (Dukes' B/C), prior treatments, operative outcomes, and survival.

Main Results:

  • Operative mortality decreased over time (20.8% overall to 9% in the last decade).

Related Experiment Videos

  • Morbidity rate was 26.3%, with prior treatment being a predictor of complications.
  • Overall 5-year survival was 41.6%, with higher recurrence rates in Dukes' C (57%) versus Dukes' B (27%) lesions.

    • Conclusions:

    • Total pelvic exenteration is a viable option for selected, primary, locally advanced rectosigmoid cancers in good-risk patients.
    • The procedure can be performed with acceptable morbidity and mortality, offering a >40% 5-year survival.
    • Prior treatment significantly impacts morbidity; age and nodal status may influence outcomes but require further study.