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Acupoint Application Combined with Acupressure as an Adjunctive Therapy for Chemotherapy-Induced Nausea and Vomiting
Published on: June 21, 2024
980
Previous chemotherapy can cause PONV
Yesim Cokay Abut1, Kubra Bolat1, Nurten Yanık1
1Department of Anestesiology and Reanimation, University of Health Sciences Istanbul Education and Training Hospital, Turkey.
Summary
Previous chemotherapy may increase the risk of postoperative nausea and vomiting (PONV) in breast cancer patients. This study highlights a potential link requiring further investigation into managing PONV in these patients.
Area of Science:
- Anesthesiology
- Oncology
- Surgical Care
Background:
- Postoperative nausea and vomiting (PONV) and chemotherapy-induced nausea and vomiting (CINV) share similar mechanisms but their interactions are understudied.
- Understanding these interactions is crucial for improving patient outcomes after cancer surgery.
Purpose of the Study:
- To investigate the effect of prior chemotherapy on the incidence and severity of PONV in breast cancer patients undergoing surgery.
- To identify potential risk factors for PONV in this specific patient population.
Main Methods:
- A prospective observational study involving 143 female breast cancer patients (ASA I-II, aged 18-65).
- Standardized anesthesia induction and maintenance protocols were used.
- PONV intensity was assessed at 2-24 hours post-extubation using defined criteria for mild, moderate, and severe symptoms.
Main Results:
- Analysis of data from 143 patients revealed a significantly higher prevalence of nausea and vomiting between 2-24 hours postoperatively in patients with a history of chemotherapy (p < 0.05).
Conclusions:
- Previous chemotherapy administration appears to be a significant risk factor for developing postoperative nausea and vomiting.
- Further research is warranted to elucidate the mechanisms and develop targeted interventions for PONV in patients with a history of chemotherapy.
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