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A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
Published on: September 30, 2021
Clinical practice guideline and real-life practice in hepatocellular carcinoma: A Korean perspective
Myung Ji Goh1, Dong Hyun Sinn1, Jong Man Kim2
1Division of Gastroenterology and Hepatology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Insights
South Korea
Area of Science:
- Hepatology
- Oncology
- Clinical Practice Guidelines
Background:
- Hepatocellular carcinoma (HCC) presents a significant global health challenge, particularly in South Korea.
- Existing practice guidelines aim to standardize HCC management.
- Discrepancies often exist between established guidelines and actual clinical practice.
Purpose of the Study:
- To review key recommendations from the 2022 Korean practice guidelines for HCC management.
- To examine the current clinical landscape of HCC treatment in South Korea.
- To identify strategies for bridging the gap between guideline recommendations and real-world patient care.
Main Methods:
- Review of the 2022 Korean Liver Cancer Association and National Cancer Center Korea Practice Guideline Revision Committee guidelines.
- Analysis of real-world clinical data and practices in South Korea concerning HCC.
- Comparative discussion of guideline-based versus actual clinical approaches.
Main Results:
- Key recommendations from the 2022 HCC guidelines are presented.
- The current clinical situation for HCC management in South Korea is described.
- Specific areas where clinical practice deviates from guidelines are highlighted.
Conclusions:
- Aligning clinical practice with updated HCC guidelines is crucial for improving patient outcomes.
- Addressing the identified discrepancies requires targeted interventions and education.
- Continued efforts are needed to ensure evidence-based care for HCC patients in South Korea.
Abstract:
Hepatocellular carcinoma (HCC) is a major cause of death in many countries, including South Korea. To provide useful and sensible advice for clinical management of patients with HCC, the Korean Liver Cancer Association and National Cancer Center Korea Practice Guideline Revision Committee have recently revised the practice guidelines for HCC management. However, there are some differences between practice guidelines and real-life clinical practice. In this review, we describe some key recommendations of the 2022 version of practice guidelines and the real-life clinical situation in South Korea, together with discussion about efforts needed to reduce the difference between guidelines and real-life clinical practice.
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