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Radiological Outcome of Neurocysticercosis in Children Six Months After Diagnosis - A Single Center Study
Parthiban Shanmugavel1, Rachna Sehgal2, Ritu Nair Misra3
1Department of Pediatrics, VMMC and Safdarjung Hospital, New Delhi.
Insights
In children with neurocysticercosis, over half showed lesion calcification by six months. Initial perilesional edema predicted this calcification, aiding in understanding disease progression.
Area of Science:
- Neurology
- Infectious Diseases
- Pediatrics
Background:
- Neurocysticercosis is a significant cause of neurological disease in children.
- Understanding lesion evolution, including calcification, is crucial for management.
- Predictors of calcification in pediatric neurocysticercosis require further elucidation.
Purpose of the Study:
- To determine the proportion of children with neurocysticercosis who develop lesion calcification at six months.
- To identify predictors of lesion calcification in this pediatric cohort.
Main Methods:
- Children aged 2-12 years with neurocysticercosis diagnosed via MRI brain were enrolled.
- A six-month follow-up included repeat CECT brain to assess lesion status (persistence, calcification, or resolution).
Main Results:
- Calcification was observed in 16 out of 30 patients (53.3%) at the six-month follow-up.
- Perilesional edema at initial presentation was significantly associated with lesion calcification at six months (P=0.042).
Conclusions:
- Perilesional edema is a significant predictor of lesion calcification in children with neurocysticercosis.
- These findings highlight the importance of initial imaging findings in predicting long-term outcomes.
Objective:
To assess proportion and predictors of lesion calcification in children aged 2-12 years with neurocysticercosis at six months follow up.
Methods:
Children aged between 2 and 12 years with Neurocysticercosis diagnosed on MRI brain were initially included and followed up for 6 months. Repeat CECT brain at 6 months was done to find if the lesion persisted/calcified/ resolved.
Results:
16 out of 30 patients (53.3%) had calcification at six months follow up. Perilesional edema at the initial stage of the presentation was significantly associated with calcification at 6 months (P=0.042).
Conclusions:
Perilesional edema at the time of presentation was significantly associated with calcification in children with neurocysticercosis, six months after diagnosis.
