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Author Spotlight: Developing a Point-of-Care Hemoglobin Estimation Method for Anemia Management
Published on: January 19, 2024
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Non-invasive hemoglobin estimation for preoperative anemia screening.
Kevin D Hornedo-González1,2, Adam K Jacob1,3, Jennifer M Burt1,4
1Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Transfusion
|January 6, 2023
Summary
Non-invasive hemoglobin estimation (SpHb) can help screen surgical patients for anemia, potentially avoiding blood draws. This method shows promise for reliably ruling out anemia, improving preoperative care.
Area of Science:
- Anesthesiology
- Perioperative Medicine
- Medical Devices
Background:
- Preoperative anemia is prevalent and linked to poor surgical outcomes.
- Traditional hemoglobin assessment via phlebotomy causes discomfort and blood loss.
- Non-invasive hemoglobin estimation offers an attractive alternative for preoperative screening.
Purpose of the Study:
- To evaluate the feasibility and accuracy of non-invasive hemoglobin estimation (SpHb) for preoperative anemia screening.
- To compare SpHb measurements with traditional complete blood count (CBC) hemoglobin levels.
- To determine an optimal SpHb threshold for identifying anemia in surgical patients.
Main Methods:
- Prospective study of adult patients undergoing elective surgery.
- Masimo Pronto Pulse CO-Oximeter used for non-invasive SpHb measurements.
- Receiver operating characteristic (ROC) curve analysis to determine optimal SpHb cut-point for anemia detection.
Main Results:
- SpHb measurements were obtained in 92% of 122 patients.
- SpHb generally overestimated hemoglobin levels.
- An optimal SpHb cut-point of 13.5 g/dL demonstrated 86% sensitivity and 81% specificity for anemia detection.
- This approach could have potentially avoided phlebotomy in 60% of patients while missing fewer than 3% of anemia cases.
Conclusions:
- Non-invasive hemoglobin estimation (SpHb) is a feasible tool for preoperative anemia screening in surgical patients.
- SpHb devices show potential for reliably ruling out anemia, despite some accuracy limitations.
- This technology may reduce unnecessary phlebotomy and improve the preoperative assessment process.

