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Published on: October 17, 2018
Correlation between gray values in cone-beam computed tomography and histomorphometric analysis
Najmeh Anbiaee1, Reihaneh Shafieian2, Farid Shiezadeh3
1Department of Oral and Maxillofacial Radiology, Dental Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
Purpose:
The aim of this study was to analyze the relationships between bone density measurements obtained using cone-beam computed tomography (CBCT) and morphometric parameters of bone determined by histomorphometric analysis.
Materials And Methods:
In this in vivo study, 30 samples from the maxillary bones of 7 sheep were acquired using a trephine. The bone samples were returned to their original sites, and the sheep heads were imaged using CBCT. On the CBCT images, gray values were calculated. In the histomorphometric analysis, the total bone volume, the trabecular bone volume (referred to simply as bone volume), and the trabecular thickness were assessed.
Results:
Statistical testing showed significant correlations between CBCT gray values and total bone volume (r=0.537, P=0.002), bone volume (r=0.672, P<0.001), and trabecular thickness (r=0.692, P<0.001), as determined via the histomorphometric analysis.
Conclusion:
The results indicate a significant and acceptable association between CBCT gray values and bone volume, suggesting that CBCT may be used in bone densitometry.
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