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Updated: Aug 16, 2026

Generation of Human 3D Lung Tissue Cultures 3D-LTCs for Disease Modeling
Published on: February 12, 2019
Fulminant sepsis secondary to severe lung contusion from the Lund University Cardiopulmonary Assist System device
1Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.
Introduction:
Portable mechanical chest compression devices have been developed to improve upon many problems of manual compression, increase patient survival, and improve neurologic outcomes. However, the use of these devices is not without risk of harm to the patient.
Case Report:
We describe a patient who received chest compressions from a mechanical compression device after cardiac arrest and subsequently developed fulminant sepsis secondary to lung contusions and a necrotizing pulmonary infection.
Discussion:
Although injuries from the LUCAS have been reported, we believe this is the first reported fatal complication related to direct pulmonary injury from a mechanical compression device.
Conclusion:
More investigation is needed to determine the safety and efficacy of the LUCAS especially in obese patients.
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