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Amphetamines modulate fentanyl-depressed respiration in a bidirectional manner.

Harrison J Elder1, Neil B Varshneya2, D Matthew Walentiny1

  • 1Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.

Drug and Alcohol Dependence
|January 6, 2023
PubMed
Summary

Fentanyl co-use with amphetamines may worsen respiratory depression. However, amphetamines might also reverse fentanyl-induced respiratory issues, offering potential overdose mitigation strategies.

Keywords:
AmphetamineCo-useFentanylMethamphetamineNaloxoneRespiration

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