Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

56
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
56
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

18
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
18
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

41
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
41
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

57
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
57

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Deep Learning for Cardiac Image Analysis: Unveiling Advances in Deep Learning Architectures.

JACC. Cardiovascular imaging·2026
Same author

Deep generative models for vessel segmentation in CT angiography of the brain.

Computers in biology and medicine·2026
Same author

Patients with persistent atrial fibrillation and metabolic comorbidities have an altered inflammatory state of atrial epicardial adipose tissue, which is linked to CT-attenuation.

Cardiovascular diabetology·2025
Same author

Artificial intelligence-based identification of thin-cap fibroatheromas and clinical outcomes: the PECTUS-AI study.

European heart journal·2025
Same author

Automated mitral valve segmentation in PLAX-view transthoracic echocardiography for anatomical assessment and risk stratification.

Computers in biology and medicine·2025
Same author

Brain age identification from diffusion MRI synergistically predicts neurodegenerative disease.

Imaging neuroscience (Cambridge, Mass.)·2025
Same journal

Discrimination of plaque from sluggish-flow-related hyperintense artifact on high-resolution magnetic resonance vessel wall imaging.

European journal of radiology·2026
Same journal

MRI-based quantification of intratumoral heterogeneity for differentiating glioblastoma from solitary brain metastasis: a two-center study.

European journal of radiology·2026
Same journal

MRI/MRCP and endoscopic ultrasound in pancreatobiliary disease: defining complementary roles in diagnostic and therapeutic decision-making.

European journal of radiology·2026
Same journal

Left atrial geometry in atrial Fibrillation: A comparison between electroanatomical mapping and computed tomography.

European journal of radiology·2026
Same journal

Enhancing pancreatic imaging in CT - prospective comparison of fixed versus individualized post-trigger delay in bolus tracking.

European journal of radiology·2026
Same journal

Ultrasound elastography of the liver and spleen in postoperative monitoring after abdominal surgery: A radiological perspective.

European journal of radiology·2026
See all related articles

Related Experiment Video

Updated: Aug 15, 2025

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
04:40

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans

Published on: August 28, 2018

15.3K

Aortic calcification: A postmortem CT validation study in a middle-aged population.

Annelotte Vos1, Ignas B Houben2, Csilla Celeng3

  • 1University Medical Center Utrecht and Utrecht University, Department of Pathology, The Netherlands.

European Journal of Radiology
|January 7, 2023
PubMed
Summary
This summary is machine-generated.

Computed tomography (CT) accurately detects aortic calcifications, primarily located in the intimal layer of the abdominal aorta. This finding validates CT

Keywords:
Abdominal aortaAtherosclerosisCalcificationsIntimal lesions

More Related Videos

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
08:43

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation

Published on: May 31, 2016

19.7K
Author Spotlight: Enhanced Quantification of Cardiovascular Calcification Progression for Longitudinal Micro PET/CT Studies in Small Research Animals
08:02

Author Spotlight: Enhanced Quantification of Cardiovascular Calcification Progression for Longitudinal Micro PET/CT Studies in Small Research Animals

Published on: November 15, 2024

687

Related Experiment Videos

Last Updated: Aug 15, 2025

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
04:40

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans

Published on: August 28, 2018

15.3K
Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
08:43

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation

Published on: May 31, 2016

19.7K
Author Spotlight: Enhanced Quantification of Cardiovascular Calcification Progression for Longitudinal Micro PET/CT Studies in Small Research Animals
08:02

Author Spotlight: Enhanced Quantification of Cardiovascular Calcification Progression for Longitudinal Micro PET/CT Studies in Small Research Animals

Published on: November 15, 2024

687

Area of Science:

  • Cardiovascular Imaging
  • Histopathology
  • Atherosclerosis Research

Background:

  • Aortic calcification detected by computed tomography (CT) is a significant predictor of cardiovascular mortality, all-cause mortality, and cognitive decline.
  • Previous studies have presented conflicting evidence regarding the precise location of aortic calcifications within the aortic wall layers (medial vs. intimal).
  • Understanding the histological basis of CT-detected aortic calcifications is crucial for accurate interpretation and risk stratification.

Purpose of the Study:

  • To histologically validate the detectability and precise location of aortic calcifications identified on computed tomography (CT) within the aortic wall.
  • To correlate CT findings of aortic calcification with detailed histological analysis of postmortem aortic tissue samples.

Main Methods:

  • Acquisition of postmortem CT images from 40 individuals.
  • Collection and histological examination (hematoxylin and eosin, elastic van Gieson stain) of 170 aortic tissue samples from five distinct locations.
  • Manual annotation of calcifications in the intima and media, with subsequent scoring of presence and morphology on CT images.

Main Results:

  • Aortic calcifications were identified in 44% of the analyzed samples, with a higher prevalence in the abdominal aorta compared to the thoracic aorta.
  • Overwhelmingly (99%), observed calcifications were located in the intimal layer, with only a small fraction showing medial involvement.
  • CT imaging demonstrated an 85% concordance with histological findings for the presence of calcifications and high agreement for annularity (kappa=0.68).

Conclusions:

  • Computed tomography (CT) reliably detects aortic calcifications, which are predominantly located in the intimal layer of the abdominal aorta in non-aneurysmatic and non-dissected aortas.
  • The presence and annular characteristics of aortic calcifications can be accurately assessed using CT imaging.
  • These findings support the use of CT for evaluating aortic calcification and its association with cardiovascular risk.