Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Polyfunctionalized <i>N</i>-Arylsulfonyl Indoles: Identification of (<i>E</i>)-<i>N</i>-Hydroxy-3-{3-[(5-(3-(piperidin-1-yl)propoxy]-1<i>H</i>-indol-1-yl)sulfonyl]phenyl}acrylamide (MTP150) for the Epigenetic-Based Therapy of Parkinson's Disease.

International journal of molecular sciences·2026
Same author

Virtual Reality-Based Dichoptic Therapy in Acquired Brain Injury: Functional and Symptom Outcomes.

Journal of clinical medicine·2026
Same author

Neuroprotective and Antioxidant Properties of Different Novel Steroid-Derived Nitrones and Oximes on Cerebral Ischemia In Vitro.

International journal of molecular sciences·2025
Same author

Synergistic interaction between praziquantel and oxfendazole or fenbendazole in a murine cysticercosis model.

Antimicrobial agents and chemotherapy·2025
Same author

In Vivo Evidence of Melatonin's Protective Role in Alkylating-Agent-Induced Pulmonary Toxicity: A Systematic Review.

Antioxidants (Basel, Switzerland)·2025
Same author

Did Serendipity Contribute to the Discovery of New Antidepressant Drugs? Historical Analysis Using Operational Criteria.

Alpha psychiatry·2025

Related Experiment Video

Updated: Aug 15, 2025

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
08:22

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

4.2K

Decrease Retinal Thickness in Patients with Chronic Migraine Evaluated by Optical Coherence Tomography.

Isidoro Raga-Martínez1,2, Francisco J Povedano-Montero3,4,5, Jesús Hernández-Gallego6,7

  • 1Faculty of Health Sciences, University Camilo José Cela, 28692 Madrid, Spain.

Diagnostics (Basel, Switzerland)
|January 8, 2023
PubMed
Summary
This summary is machine-generated.

Chronic migraines are linked to reduced retinal nerve fibre layer and macular thickness. Optical coherence tomography (OCT) can detect these changes, potentially aiding in diagnosis and monitoring.

Keywords:
chronic migraineneurological disorderoptical coherence tomographyretina

More Related Videos

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
07:23

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

Published on: March 26, 2020

7.6K
Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography
03:35

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography

Published on: December 1, 2023

357

Related Experiment Videos

Last Updated: Aug 15, 2025

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
08:22

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

4.2K
Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
07:23

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

Published on: March 26, 2020

7.6K
Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography
03:35

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography

Published on: December 1, 2023

357

Area of Science:

  • Ophthalmology
  • Neurology
  • Medical Imaging

Background:

  • Chronic migraines are a neurological condition affecting millions worldwide.
  • Retinal changes may serve as indicators for neurological disorders.
  • Optical coherence tomography (OCT) is a non-invasive imaging technique.

Purpose of the Study:

  • To investigate alterations in retinal nerve fibre layer (RNFL) and macular thickness in chronic migraine patients.
  • To compare retinal layer thickness between chronic migraine sufferers and healthy individuals.
  • To assess the utility of OCT in evaluating chronic migraine-related ocular changes.

Main Methods:

  • An observational, cross-sectional study involving 90 chronic migraine patients and 90 healthy controls (aged 18-65).
  • Retinal thickness measurements were performed using spectral domain OCT (SD-OCT).
  • Evaluated peripapillary RNFL, macular RNFL, and ganglion cell layer (GCL) thickness.

Main Results:

  • Patients with chronic migraines exhibited significantly thinner RNFL (superior quadrant) compared to controls (p ≤ 0.05).
  • Mean macular thickness, macular RNFL, and GCL thickness were also significantly reduced in the chronic migraine group.
  • These findings indicate a detectable decrease in retinal thickness associated with chronic migraines.

Conclusions:

  • Chronic migraines are associated with measurable reductions in retinal thickness.
  • OCT is a valuable tool for detecting these ocular changes.
  • Quantification of axonal damage via OCT may serve as a potential biomarker for diagnosing and monitoring chronic migraines.