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Related Experiment Video

Updated: Aug 15, 2025

Clinicopathological Analysis of miRNA Expression in Breast Cancer Tissues by Using miRNA In Situ Hybridization
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Passive Microwave Radiometry and microRNA Detection for Breast Cancer Diagnostics.

Leonid Fisher1, Olga Fisher1, Dmitry Chebanov2

  • 1Russian Academy of Medico-Social Rehabilitation, Moscow 105037, Russia.

Diagnostics (Basel, Switzerland)
|January 8, 2023
PubMed
Summary
This summary is machine-generated.

Novel breast cancer screening methods, including microwave radiometry (MWR) and microRNA (miRNA) analysis, offer faster predictions than traditional mammography. These advanced techniques show promise for improving early breast cancer diagnosis.

Keywords:
breast cancerearly diagnosticsmicroRNA (miRNA)passive microwave radiometry (MWR)

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Area of Science:

  • Oncology
  • Biomedical Engineering
  • Molecular Diagnostics

Background:

  • Breast cancer remains a significant global health concern for women.
  • Early detection is crucial for effective treatment and improved patient outcomes.
  • Conventional screening methods like mammography and ultrasound have limitations in speed and accessibility.

Purpose of the Study:

  • To compare the efficacy of conventional breast cancer screening techniques with novel approaches.
  • To evaluate the potential of passive microwave radiometry (MWR) and microRNA (miRNA) analysis for early breast cancer detection.
  • To explore the combined utility of MWR and miRNA for enhanced diagnostic accuracy.

Main Methods:

  • Comparative analysis of mammography and ultrasound with passive microwave radiometry (MWR).
  • Integration of microRNA (miRNA) analysis with MWR for diagnostic improvement.
  • Assessment of prediction timelines for each screening modality.

Main Results:

  • MWR demonstrated significantly faster prediction times (weeks/days) compared to mammography (3-6 months).
  • MWR shows potential for early breast cancer detection.
  • Combining MWR with miRNA diagnostics may further enhance predictive capabilities.

Conclusions:

  • Passive microwave radiometry (MWR) offers a faster alternative for breast cancer screening.
  • MicroRNA (miRNA) analysis can complement MWR to improve diagnostic accuracy.
  • These novel techniques, alone or combined, hold promise for advancing early breast cancer diagnosis.