Related Experiment Video
Updated: Aug 15, 2025
06:40
Synthesis of a Water-soluble Metal–Organic Complex Array
Published on: October 8, 2016
9.9K
Peptide-Based Materials That Exploit Metal Coordination
Giovanni A Bassan1, Silvia Marchesan1
1Chemical and Pharmaceutical Sciences Department, University of Trieste, 34127 Trieste, Italy.
International Journal of Molecular Sciences
|January 8, 2023
Summary
This review highlights recent advances in using metal-ion coordination with peptides to create functional materials. These peptide-metal complexes show promise for applications in medicine, sensing, and environmental remediation.
Area of Science:
- Supramolecular chemistry
- Materials science
- Biotechnology
Background:
- Metal-ion coordination is a key strategy for designing functional materials.
- Peptides offer diverse metal-binding capabilities and are biocompatible/biodegradable.
- Peptide-metal complexes have potential in medicine, sensing, and environmental applications.
Purpose of the Study:
- To review the progress in metal-ion coordination with peptides over the last five years.
- To provide an overview of future research directions in this field.
Main Methods:
- Literature review of scientific publications from the past five years.
- Analysis of studies focusing on metal-ion coordination with peptides for functional material development.
Main Results:
- Significant advancements in controlling supramolecular behavior through peptide-metal interactions.
- Emerging applications in targeted drug delivery, biosensing, and pollutant degradation.
- Development of novel peptide-based materials with tailored properties.
Conclusions:
- Metal-ion coordination with peptides is a rapidly advancing field with substantial potential.
- Future research will likely focus on enhancing material functionality and expanding application scope.
- Interdisciplinary approaches combining chemistry, biology, and engineering are crucial for future progress.
Keywords:
complexescoordinationdrug deliveryenvironmental remediationmaterialsmetalsnanostructurespeptidespollutant removalsensingMore Related Videos
Related Concept Videos
02:51Metal-Ligand Bonds
21.3K
The hemoglobin in the blood, the chlorophyll in green plants, vitamin B-12, and the catalyst used in the manufacture of polyethylene all contain coordination compounds. Ions of the metals, especially the transition metals, are likely to form complexes.
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
21.3K
01:19Complexation Equilibria: The Chelate Effect
590
In complexation reactions, metal atoms or cations interact with ligands to form donor-acceptor adducts called metal complexes. Ligands that bind through one donor site are monodentate, ligands with two donor sites are bidentate, and those with more than two donor sites are polydentate ligands. For example, ethylene diamine is a bidentate ligand that binds through two nitrogen donor atoms, forming a five-membered ring. EDTA is a polydentate ligand that binds through four oxygen and two nitrogen...
590
02:42Valence Bond Theory
9.0K
Coordination compounds and complexes exhibit different colors, geometries, and magnetic behavior, depending on the metal atom/ion and ligands from which they are composed. In an attempt to explain the bonding and structure of coordination complexes, Linus Pauling proposed the valence bond theory, or VBT, using the concepts of hybridization and the overlapping of the atomic orbitals. According to VBT, the central metal atom or ion (Lewis acid) hybridizes to provide empty orbitals of suitable...
9.0K
02:54Coordination Compounds and Nomenclature
22.0K
In most main group element compounds, the valence electrons of the isolated atoms combine to form chemical bonds that satisfy the octet rule. For instance, the four valence electrons of carbon overlap with electrons from four hydrogen atoms to form CH4. The one valence electron leaves sodium and adds to the seven valence electrons of chlorine to form the ionic formula unit NaCl (Figure 1a). Transition metals do not normally bond in this fashion. They primarily form coordinate covalent bonds, a...
22.0K
00:43Complexometric Titration: Ligands
1.1K
Different monodentate and polydentate ligands are used as complexing agents in complexometric titration reactions. The formation of complexes by mono- and bidentate ligands involves two or more intermediate steps, limiting their use as complexing agents. In comparison, polydentate ligands can form complexes with metal ions in a single-step process, facilitating sharper end points. This means polydentate ligands, such as amino carboxylic acid derivatives, are most commonly employed in...
1.1K
02:57Coordination Number and Geometry
16.4K
For transition metal complexes, the coordination number determines the geometry around the central metal ion. Table 1 compares coordination numbers to molecular geometry. The most common structures of the complexes in coordination compounds are octahedral, tetrahedral, and square planar.
16.4K