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Updated: Aug 15, 2025

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
Predictors of Effectiveness and Adherence in a Multimodal Obesity Treatment Program for Children and Adolescents in
Julius Lars Breinker1, Anika Kaspar2, Elena Sergeyev2
1Integrated Research and Treatment Center Adiposity Diseases, Behavioral Medicine Research Unit, Department of Psychosomatic Medicine and Psychotherapy, University of Leipzig Medical Center, 04103 Leipzig, Germany.
Abstract:
Multimodal obesity treatments for children and adolescents generally showed only small to modest treatment effects and high dropout rates. Potential variations by patients' clinical and sociodemographic factors remain, however, largely unclear. For this reason, our study analyzed psychological, physical, and sociodemographic predictors of treatment success and adherence in a multimodal obesity treatment over 12 months. The intent-to-treat sample included n = 361 children and adolescents (ages 3-17 years), of which n = 214 or 59.28% of patients completed treatment. A younger age and, in the sensitivity analysis, additionally a greater eating disorder psychopathology and treatment initiation before COVID-19 pandemic predicted greater BMI-SDS reductions (Body Mass Index-Standard Deviation Score). In contrast, predictors of treatment adherence were not found. The results underline the importance of early treatment of juvenile obesity. Additionally, eating disorder psychopathology includes restrained eating, which implies the ability to self-regulate eating behavior and therefore may have a positive effect on the treatment goal of controlled food intake. Challenges from altered treatment procedures due to the COVID-19 pandemic nonetheless remain.
Insights
Early intervention in childhood obesity is crucial. Younger children with greater eating disorder psychopathology showed better BMI-SDS reductions in a 12-month multimodal treatment study.
Area of Science:
- Pediatric Endocrinology
- Child Psychology
- Obesity Research
Background:
- Multimodal obesity treatments for youth yield limited effects and high dropout rates.
- Predictors of treatment success and adherence in pediatric obesity are not well understood.
Purpose of the Study:
- To identify psychological, physical, and sociodemographic predictors of treatment success and adherence.
- To analyze factors influencing Body Mass Index-Standard Deviation Score (BMI-SDS) reduction in a 12-month multimodal obesity intervention.
Main Methods:
- Analysis of an intent-to-treat sample of 361 children and adolescents (ages 3-17).
- Investigated predictors of BMI-SDS reduction and treatment adherence over 12 months.
- Included sensitivity analysis for factors like eating disorder psychopathology and pandemic timing.
Main Results:
- Younger age predicted greater BMI-SDS reduction.
- Higher eating disorder psychopathology and pre-pandemic treatment initiation also predicted greater BMI-SDS reduction.
- No significant predictors for treatment adherence were identified.
Conclusions:
- Early treatment initiation is vital for juvenile obesity management.
- Eating disorder psychopathology, including restrained eating, may positively influence treatment outcomes.
- COVID-19 pandemic altered treatment delivery, posing ongoing challenges.
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