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Related Concept Videos

Endoscopic Procedures I: Esophagogastroduodenoscopy01:29

Endoscopic Procedures I: Esophagogastroduodenoscopy

319
An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
319
Endoscopic Procedures III: Video Capsule Endoscopy01:28

Endoscopic Procedures III: Video Capsule Endoscopy

293
Capsule endoscopy, or wireless or video capsule endoscopy, is a diagnostic procedure for examining the entire gastrointestinal tract. Patients swallow a capsule about the size of a vitamin tablet. The capsule is equipped with a transmitter, a battery, an LED light source, and a color video camera to capture images throughout the gastrointestinal tract. This procedure is particularly useful for diagnosing conditions such as Crohn's disease, ulcerative colitis, tumors, polyps, ulcers,...
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Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

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Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
144
Endoscopic Procedures II: Colonoscopy01:25

Endoscopic Procedures II: Colonoscopy

168
The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
168
Endoscopic Procedures V: ERCP01:26

Endoscopic Procedures V: ERCP

691
Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...
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Ultrasound II: Endoscopic Ultrasound and FibroScan01:25

Ultrasound II: Endoscopic Ultrasound and FibroScan

168
Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):
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Related Experiment Video

Updated: Aug 14, 2025

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
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Submucosal endoscopy: the present and future.

Zaheer Nabi1, Duvvur Nageshwar Reddy1

  • 1Asian Institute of Gastroenterology, Hyderabad, India.

Clinical Endoscopy
|January 8, 2023
PubMed
Summary
This summary is machine-generated.

Submucosal endoscopy, a minimally invasive technique, offers therapeutic interventions within the gastrointestinal tract. This review explores its current applications, including achalasia, tumors, and gastroparesis, and future potential.

Keywords:
EndoscopyEsophageal achalasiaMyotomyZenker diverticulum

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Area of Science:

  • Gastroenterology
  • Minimally Invasive Surgery
  • Endoscopic Therapeutics

Background:

  • Submucosal endoscopy, or third-space endoscopy, leverages the space between mucosal and muscularis layers for gastrointestinal interventions.
  • This technique has significantly advanced therapeutic endoscopy over the past decade.
  • Its applications have expanded beyond initial uses like endoscopic myotomy.

Purpose of the Study:

  • To review the current spectrum of submucosal endoscopy applications.
  • To provide updates on recent advancements in the field.
  • To discuss the future directions and potential of submucosal endoscopy.

Main Methods:

  • Literature review focusing on submucosal endoscopy.
  • Analysis of current clinical applications and emerging indications.
  • Discussion of the technique's potential for novel procedures.

Main Results:

  • Submucosal endoscopy is established for achalasia, subepithelial tumor resection, and managing gastroparesis and Zenker's diverticulum.
  • Its long-term efficacy is still under evaluation for conditions like Zenker's diverticulum and gastroparesis.
  • Emerging uses include epiphrenic diverticulum, Hirschsprung's disease, and esophageal strictures.

Conclusions:

  • Submucosal endoscopy has revolutionized gastrointestinal interventions, with established utility in several conditions.
  • Further research is needed to confirm long-term outcomes for certain indications.
  • The technique holds promise for novel applications, potentially revitalizing natural orifice transluminal endoscopic surgery.